What is the definition of primary osteoporosis?

• A. A condition related to aging and hormonal changes
• B. A bone condition resulting from specific genetic disorders
• C. A disease caused by a deficiency in vitamin D
• D. A result of excessive physical activity

Answer: (A)

Primary osteoporosis is indeed defined as a condition primarily related to aging and hormonal changes, particularly a decrease in estrogen levels in women after menopause and a decline in testosterone in men as they age. This type of osteoporosis is characterized by a reduction in bone density and an increased risk of fractures without the presence of other underlying diseases or specific pathogenic processes.

In this context, aging plays a crucial role because, with age, there is a natural decline in bone mass due to the imbalance between bone resorption and bone formation. Hormonal changes significantly influence this balance, as sex hormones such as estrogen and testosterone are essential for maintaining bone density.

The other choices describe different bone-related conditions. Genetic disorders, vitamin D deficiency, and excessive physical activity can lead to secondary forms of osteoporosis or other bone health issues but do not define primary osteoporosis, which is solely linked to the natural aging process and hormonal shifts. Understanding the distinction between primary and secondary osteoporosis is important for effective diagnosis and treatment planning.